Wednesday, March 2, 2011

SV40. Polio, and cancer.

Wikipedia has been very helpful from time to time. Here is what it says about SV40 virus found in monkeys. Important to know since this virus was mistakenly transmitted to humans through the polio vaccines of the 1950's and 1960's. Here is what Wikipedia reports.

"The virus was first identified in 1960 in cultures of rhesus monkey kidney cells that were being used to produce polio vaccine. It was named for the effect it produced on infected green monkey cells, which developed an unusual number of vacuoles. The complete viral genome was sequenced by Walter Fiers and his team at the University of Ghent (Belgium) in 1978.[2] The virus is dormant and is asymptomatic in Rhesus monkeys. The virus has been found in many macaque populations in the wild, where it rarely causes disease. However, in monkeys that are immunodeficient—due to, for example, infection with Simian immunodeficiency virus—SV40 acts much like the human JC and BK polyomaviruses, producing kidney disease and sometimes a demyelinating disease similar to PML. In other species, particularly hamsters, SV40 causes a variety of tumors, generally sarcomas. In rats, the oncogenic SV40 Large T-antigen was used to establish a brain tumor model for PNETs and medulloblastomas.[3]

The molecular mechanisms by which the virus reproduces and alters cell function were previously unknown, and research into SV40 vastly increased biologists' understanding of gene expression and the regulation of cell growth."

Wikipedia goes on,

"Soon after its discovery, SV40 was identified in the injected form of the polio vaccine produced between 1955 and 1961. This is believed to be due to kidney cells from infected monkeys being used to amplify the vaccine virus during production. Both the Sabin vaccine (oral, live virus) and the Salk vaccine (injectable, killed virus) were affected; the technique used to inactivate the polio virus in the Salk vaccine, by means of formaldehyde, did not reliably kill SV40.

It was difficult to detect small quantities of virus until the advent of PCR; since then, stored samples of vaccine made after 1962 have tested negative for SV40, but no samples prior to 1962 could be found. Thus, although over 10 million people received the potentially contaminated batches of vaccine, there is no way to know whether they were exposed to the virus, and if so, whether it was in a quantity and by a route that would cause infection. It is also unknown how widespread the virus was among humans before the 1950s, though one study found that 12% of a sample of German medical students in 1952 had SV40 antibodies. Although horizontal transmission between people has been proposed, is not clear if this actually happens and if it does, how frequently it occurs.[14]

An analysis presented at the Vaccine Cell Substrate Conference in 2004[15] suggested that vaccines used in the former Soviet bloc countries, China, Japan, and Africa, could have been contaminated up to 1980, meaning that hundreds of millions more could have been exposed to the virus unknowingly."

Having read books on this subject I can tell you that the SV40 virus can pass from generation to generation. Meaning, if the father got it from the vaccine he could give the virus to his children. SV40 virus infected the polio vaccine due to the fact they used to breed the virus in monkey kidneys. Lets turn back to wikipedia.

"Glioblastoma multiforme (GBM) is the most common and most aggressive type of primary brain tumor in humans, involving glial cells and accounting for 52% of all parenchymal brain tumor cases and 20% of all intracranial tumors. Despite being the most prevalent form of primary brain tumor, GBMs occur in only 2–3 cases per 100,000 people in Europe and North America. According to the WHO classification of the tumors of the central nervous system‎, the standard name for this brain tumor is "glioblastoma"; it presents two variants: giant cell glioblastoma and gliosarcoma. Glioblastomas are also an important brain tumor of the canine, and research is ongoing to use this as a model for developing treatments in humans.[1] Treatment can involve chemotherapy, radiation, radiosurgery, corticosteroids, antiangiogenic therapy, and surgery.[2]

Excepting the brainstem gliomas, glioblastoma has the worst prognosis of any CNS malignancy. Despite multimodality treatment consisting of open craniotomy with surgical resection of as much of the tumor as possible, followed by concurrent or sequential chemoradiotherapy, antiangiogenic therapy with bevacizumab, gamma knife radiosurgery, and symptomatic care with corticosteroids, median survival is about 14 months.[3]"

So what does this have to do with the polio virus and SV40? Lets keep reading wikipedia.

"GBM is more common in males, although the reason for this is not clear.[4] Most glioblastoma tumors appear to be sporadic, without any genetic predisposition. No links have been found between glioblastoma and smoking,[5] diet,[6] cellular phones,[7] or electromagnetic fields.[8] Recently, evidence for a viral cause has been discovered, possibly SV40[9] or cytomegalovirus.[10] There also appears to be a small link between ionizing radiation and glioblastoma.[11] Some also believe that there may be a link between polyvinyl chloride (which is commonly used in construction) and glioblastoma.[12] A recent link cited in the Lancet medical journal links brain cancer to lead exposure in the work place.[13] There is an association of brain tumor incidence and malaria, suggesting that the anopheles mosquito, the carrier of malaria, might transmit a virus or other agent that could cause glioblastoma.[14]"

Did you catch the middle section there? "Recently, evidence for a viral cause has been discovered, possibly SV40 or cytomegalovirus." Hmmmm. Well, we don't know for sure if the SV40 causes glioblastoma, but it could. What I can tell you is that I know that the sv40 virus does cause cancer. Dr. Eisenstein has covered this in his books, and even the vaccine manufacturers themselves have admitted it (albeit in a back handed way).

Most who will read this know that I am a nurse and have a healthy (albeit not one size fits all) perspective on vaccines. However, this is the first time in my life where a vaccine could have (not saying it did) harmed a loved one of mine. My cousin (who will remain nameless as I don't feel giving that information is appropriate) just got diagnosed with a glioblastoma in his early 40's. A God fearing man, one who loves his family and takes care of them. He has children, and is a jem of a person. Is it too much to ask that we find out if this vaccine had anything to do with this? Am I going to say any of this to my cousin? Probably not. At least not now. But i would love to get some answers. And if this vaccine could have caused this i would love to have a little accountability. Again, not saying the vaccine is responsible (an important point). We don't know enough. But one does question.


Stephen T. McCarthy said...

Pretty interesting stuffs, BR'ER. You're definitely my "go-to" guy when it comes to vaccines and medical issues.

And I'm glad to see you coming around a little more often again. Ya know, one must have SOME occasional hobbies. As they say... "All wife 'n' kids and no blogging makes Marc a dull boy."

Well, that's the way I first heard it anyway. ;o)

~ D-FensDogg
'Loyal American Underground'

mousiemarc said...

Thank you, and I do hope to contribute here a little more. Who knows though. It just depends on my other projects (of which I have many). Thank you for your kind words though. Much appreciated.